Products for the Treatment of F.P.T. in the Equine NeonateHiGAMM EQUI and FOALIMMUNE
1. USDA licensed
2. Quantified IgG content
HiGamm-Equi >= 2500mg/dl
Foalimmune >= 1750mg/dl
3. Proven efficacy when dosed at 15ml/lb HiGamm-equi will produce a rise in IgG to 600mg or greater in the healthy foal. 
4. 3 year frozen shelf life and free replacement for outdates or damaged bags.
5. Single universal donor source - reduces foreign protein exposure - unlike batched donor serum products which expose the recipient to more foreign proteins.
HiGamm-Equi- No other IgG product has demostrated such a large increase in foal IgG
at 24 and 48 hours after oral or intravenous administration
Mean IgG rise at 24 hours = 1042.74 mg/dlFPT EFFICACY We've proven it! We Guarantee it! 1999 Colostrum Deprived Foal Receiving Non-Irradiated Plasma
FOAL IgG Values 24 hours  and 48 hours of age 
Yellow line is Mean IgG rise
product - Equine IgG = 2000 mg/dl, dose 20 ml/lb, Mean IgG rise at 24 hours = 1042.74 mg/dl
Materials, Methods and Conclusions
All foals were separated from their dams at birth and kept separated for 24
hours. Foals were not allowed to nurse during the first 24 hours. Equine
IgG was administered shortly after birth. Blood samples were taken prior to
the administration of Equine IgG - 0 hour, at 24 hours, and at 48 hours for
IgG determination. IgG values on all samples (0 hour, 24 hour and 48 hour)
were determined by Radial Immunodiffusion (VMRD) Equine RID.
The 24 and 48-hour IgG values are plotted along with the NVSL species
standard (IgG = 450 ml/dl). This standard is provided by the USDA as a reference for
the minimum acceptable IgG level after FPT treatment.
Results - All foals administered Hi-Gamm Equi exceed the USDA species
standard, achieving a mean IgG rise to 1042 mg/dl at 24 hrs.
Conclusion - Hi-Gamm Equi provides adequate treatment for FPT and there is
no significant difference in IgG rise when foals nursed colostrum after 24
hours of age. The 48-hour IgG values resulting from this trial indicate that
there is no further absorption of IgG when the foal is allowed to nurse mare
âs colostrum at 24 hours of age. The mares were not milked during the first
24-hour period. This is confirmed by a comparison of the 24 hour and 48
hour IgG values. Mean 24 hour IgG = 1042mg/dl: Mean 48 hour IgG =
1074mg/dl.
ADVANTAGES WHEN PURCHASING EQUINE IgG PRODUCTS FROM
LAKE IMMUNOGENICS INC.
1) Rapid administration 7 minutes* It takes only 15 minutes to thaw in
warm water and then it may be administered as rapidly as any other IV fluid.
As with any fluid, monitor closely during intravenous administration,
because volume overload is possible.
2) No mixing with other fluids prior to administration (like Seramune &
Lyphomune). No warnings about pretreatment with anti-inflammatory drugs
before administration (like Seramune). No time restrictions on the rate of
administration (like Seramune & Lyphomune).
3) Clear plasma - free of precipitate due to our advanced collection
technique The occurrences of reactions requiring the suspension of
administration are rare with an approximate incidence of 1 per 2000-3000
administrations
4) Guaranteed successful treatment of FPT when dosed properly.
5) Free replacement of outdates - 3 year shelf life. 6)
Reduced shipping charges on quantity orders. 7)
Lower price per gram IgG than Seramune, Lyphomune, or Polymune.
* The average administration time of 160 doses of plasma to thoroughbred
foals in a 2000 field trial
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